UroToday - This study from Italy investigated the association of vesicoureteral reflux (VUR) and renal scarring. It has been shown that children with a febrile urinary tract infection (UTI) and no VUR may have evidence of renal defects when imaged with scintigraphic studies. Therefore, it has been postulated that VUR is a weak predictor of renal defects.

The group employed isotopic cystography (IC) for diagnosis of VUR in children with febrile UTIs. Dimercaptosuccinic acid renal scintigraphy was performed 6 months after cure of the last UTI. They defined renal defects by the observation of focal defects of radionuclide uptake and/or by a split renal function

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